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Whilst low-depend MBL seldom progresses to CLL, higher-depend MBL progresses to CLL demanding therapy in a charge of one% to two% per year. Significant-count MBL is distinguished from Rai 0 CLL according to if the B-cell count is above or beneath 5 × 109/L. While individuals with the two high-depend MBL and CLL Rai stage 0 are at elevated possibil